MEDICAL MEMORANDA. I cannot get along without nuclein. It's a wonderful remedy.-Dr. J. S. D. A good remedy for relaxation of the womb and its appendages is aletris cordial (Rio); strengthens the uterine organs and at the same time corrects the co-existing general weakness. Best Results than from Any Combination.-I must say that neurosine has given better results and more universal satisfaction than any combination ever used by me. I have tried it in many nervous affections and in epilepsy of long standing. In some it is a specific, in others a therapeutic agent of great value.-W. L. Gahagan, M. D., coroner of Hamilton county, Chattanooga, Tenn. Pneumonia is now running riot throughout the winter-visited world. Physicians everywhere are putting forth their best efforts to overcome the evil effects of this disease, which is even more deadly than the great white plague. The physician who covers the thoracic walls-front, sides and back of his pneumonia patients with antiphlogistine, is the one who is actually giving his patients the very best chance of recovery. No method of external application-be it ice, hot water turpentine, or what not-has commenced to yield the beneficial results obtained from the proper application of antiphlogistine. Huston Brothers Co.-We would call the attention of our readers to the advertisement of the Huston Brothers Co. that appears in this issue. There would really appear to be many points of distinct advantage in the electrical cabinets manufactured by this firm, and we strongly advise all our readers, who are at all interested, to write for their catalogue. It has only recently come to our knowledge that the millionaire Armour family selected one of Huston's electric cabinets in preference to all others for the treatment of Lolita, the famous little patient of Dr Lorenz during his recent visit in this country. Although the Huston cabinets undoubtedly would appear to be the best on the American market, their prices are by no means the highest. Huston Brothers have recently issued a very neat, compact, little catalogue to cover this special line of goods Even if you do not think of purchasing a cabinet right away, you should at least have a catalogue so that you may get posted. Carabana recently admitted to the domain of therapeutics, has, at a bound, jumped into the first place. A mildness and certainty of its purgative action, smallness of dosage, a few contra-indications contribute to make it useful, not only as a remedy, but also as a means of diagnosis. It produces, when used as a purgative, a number of abundant, regular passages without griping. If taken in small doses for several days, continuously, it does not cause gastric or intestinal disturbances as do waters of analagous composition. In the diseases of my clinic I have had splendid results from its use; as a resolvent in chronic inflammatory affections of the prostate and vesicles, in gonorrhea; in inflammation and conjestions of the cervix uteri and in leucorrhea, carabana, taken in small doses, combined with injections and douches, speedily effects a cure. In scrofulous, glandular and cutaneous manifestations, especially in eruptions of the face and skin, have I met with success by using carabana locally and administering it in small doses. It is desirable that its employment become general, as the indications for its use, derived from a study of its chemical composition, become greater from day to day."-Prot. M. S. B, Treatment of the Throat.-Dr. E. Jay Fisk, Troy, N. Y., uses eusoma in the treatment of all forms of irritation of the throat, and states that even in follicular tonsillitis he has been surprised, as well as pleased, with the prompt and satisfactory results which he has obtained from its use. Dr. Fisk prescribes eusoma as a local application in these cases, and almost without exceptlon, immediate relief from unpleasant symptoms is obtained. Dr. Fisk also states that he gives eusoma internally in irritative disease of the skin, supplementing its internal use by the external application of the same remedy. Dr. Fisk's experience is confirmatory of that of other physicians who have studied the clinical us of echinacea. Dr. A. B. Matthews, of Elberton, Ga., in an article published in the Georgia Practitioner, May 15, 1905, states "that it promotes the flow of saliva with feeling of well-being in the stomach, and is slightly diaphoretic, increasingly if continued. The action of the kidneys and whole glandular system seems to stimulate under its influence. The stomach is improved in its function, the appetite increases, food is more perfectly digested, the bowels operate better and absorption and assimilation and general nutrition are in every way improved. It encourages secretions and excretions and in this manner prevents any further autoinfection and quickly relieves the system of any that is present. Eusoma is simply echinacea combined with the adjuvants, thuja and baptisia, and is without doubt the most reliable preparation of echinacea upon the market. Each fluid dram of eusoma contains 15 grains of echinacea, 2 grains of thuja and 4 grains of baptisia. The Eusoma Pharmaceutical Co., of Cincinnati, have collected a large amount of information with regard to echinacea, which they will be glad to mail to any physician requesting it. THIS Company sells Five per cent Interest-Bearing Gold Bonds for Savings Investment on partial payments of one dollar per week and over. Also Five per cent Interest-Bearing Gold Coupon Bonds calling for a Cash Investment of $500.00. The Gold Coupon Bonds carry semi-annual five per cent interest coupons. 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THE MAGIC OF BOOK MAKING Take Progressive Medicine for instance, which gives the story of the world's medical achievements, discoveries and advances, with frank criticisms-sometimes commendatory-sometimes adversealways with the daily needs of the practitioner in view. Consider what is involved of labor, study, care and expense. The periodicals and books in all languages and from all medical centres used by its collaborators cost several thousand dollars each year. A small regiment of authors, men who know, men who are at home with foreign languages, men who can write lucidly and interestingly, men who have the requisite clinical experience take from this mass of literature all there is of practical value and make of it a connected narrative of progress in every department. Progressive Medicine is therefore, an original, logical story, written by the brightest lights in the whole medical firmament and based upon their experiences in hospitals, laboratories and private practice. A general editor supervises all this material, arranges it, and puts it in shape for ready reference and use. Illustrations are used wherever they can serve to elucidate the text. The result is four substantial Octavo Volumes which the publishers deliver to your office for Six Dollars. Does it not seem like the effect of a touch of a magician's wand? The product of an investment of thousands of dollars is placed in your hands for Six Dollars! You could not read all the medical literature of the year if you devoted all your time to it. Progressive Medicine does this for you and sifting out the bad or doubtful gives you the good and trustworthy, ready for instant use. Series of 1906 will appear in March, June, September and December. Orders may be sent at once, but remittances need not be made until Spring, 1906. Full descriptive circular on request. LEA BROTHERS & Co., Philadelphia and New York. Vol. XXIV ST. LOUIS, FEBRUARY 10, 1906. Papers for the original department must be contributed exclusively to th's magazine, and should be in hand at least one month in advance. French and German articles will be translated free of charge, if accepted. A liberal number of extra copies will be furnished authors, and reprints may be obtained at cost, if request accompanies the proof. Engravings from photographs or pen drawings will be furnished when necessary to elucidate the text. Rejected manuscript will be returned if stamps are enclosed for this purpose. COLLABORATORS. ALBERT ABRAMS, M. D., San Francisco. ARTHUR R EDWARDS, M. D., Chicago, Ill. Mr. REGINALD HARRISON, London, England. HOBART A. HARE, M. D., Philadelphia. THOMAS LINN, M. D., Nice, France. President Tri-State Medical Society of Alabama, Georgia and Tennessee, 1905. My object in presenting this brief paper is to report two cases of this fearful malady that came under my care last year, and to try to bring out some discussion of that most virulent form of gangrene, which is so rapid in action, so fatal to life and limb, and which is known by so many names in our literature, such as "spreading traumatic gangrene, "malignant edema, "purulent edema, ' "fulminating gangrene, " "emphysematous gangrene, gangrenous emphysema, "" 'gangrene foudroyante" (French), etc., I prefer to anglicise the latter term and call it foudroyant gangrene. In this form of gangrene there must be an open wound, a restricted or occluded arterial or venous blood supply and a septic infection. The injury necessary may vary from a small scratch to a large and severe laceration, such as we so frequently meet with in dealing with those who have been hurt by machinery or in railway injuries. Crushed injuries, com *Read before the Tri-State Medical Society, Chattanooga, Tenn., September 26, 1915. No. 3 pound fractures and gunshot wounds of the limbs are especially liable to be followed by this form of gangrene. Of course, the pathogenic organism is also necessary, but experimenters have found considerable difficulty in insolating this germ, and making it fulfill all the postulates of Koch. The organism known as the "vibrion septique' of Pasteur, and called by others the bacillus of malignant edema, was formerly thought to be the real cause of this trouble, but in 1891, Welch discovered that this form of gangrene was nearly always associated with an organism known as the bacillus aerogenes capsulates; he found that if guinea-pigs were injected with fresh cultures of this bacillus, local gangrene with emphysema and even death resulted; rabbits and mice were found to have greater resistance, and generally withstood its invasion; however, when rabbits with broken bones were injected intravenously gaseous abscesses formed around the ends of the fragments, and when such animals were killed, and their bodies kept in warm surroundings, they soon underwent rapid gaseous degeneration. This probably explains why this variety of gangrene travels so rapidly, especially when hot external applications are applied to the parts affected. Recently Iacobelli has insolated a bacillus in two cases of gaseous gangrene, which is very similar to that found by Legros, and called by the latter the "septic aerobic bacillus." Iacobelli does not consider his bacillus identical with that of Welch; guinea pigs inoculated with pus from gangrenous wounds caused by this bacillus died in about twenty-four hours, but did not show any gaseous gangrene. It was also found to be very of the micro-organisms seems to be in the resistant to antiseptics. The natural habitat of soil and in the alimentary canal. Combined with the bacilli above mentioned streptococci have nearly always been found in this variety of the disease in man. When the edema begins the blood vessels are compressed and sometimes occluded, and this materially lowers the vitality of the part and gives impetus to the disease. This form of gangrene usually appears within two or three days after the patient has received a severe laceration, contusion, gunshot or some other wound which cannot be or has not been thoroughly disinfected. In some cases there are irregular chills followed by more or less fever, just as may be seen in any form of sepsis; in other cases these chills |